2 A FRAME-SHIFT VARIANT IN THE NOVEL IFNL4 GENE IS ASSOCIATED WITH IMPAIRED HCV CLEARANCE

1 ALTERED HCV SPECIFIC T CELL IMMUNITY VERY EARLY IN INTERFERON FREE HCV DAA THERAPY L. Barrett, G. Shivasabesan, C. Wang, A. Osinusi, A. Kohli, E.G. Meissner, L. Heytens, A. Nelson, M.A. Polis, H. Masur, W. Symonds, J. McHutchinson, S. Kottilil. Laboratory of Immunoregulation, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, SAIC-Frederick Inc, Frederick, CCMD, CC, National Institutes of Health, Bethesda, MD, Gilead Sciences, Inc., Foster City, CA, USA E-mail: barrettl@niaid.nih.gov