Paternal disease activity is associated with difficulty in conception among men with inflammatory bowel diseases

: The impact of inflammatory bowel disease (IBD) activity and treatment on fertility and pregnancy outcomes is important for men and women. In women, remission at conception determines better pregnancy outcomes,1,2 and most maternal IBD medication exposures are safe.2 In contrast, less is known about the impact of paternal disease activity and medication use on fertility and pregnancy outcomes in men with IBD.3.