GENOTYPIC AND PHENOTYPIC EXPRESSION OF IL2G/T AND IL-8 HELP PREDICT ESTABLISHMENT OF CLINICAL RHEUMATIC HEART DISEASE: DATA FROM THE PROVAR STUDY

The inflammatory response associated with rheumatic heart disease (RHD) is influenced by gene polymorphisms, as well as by the levels of inflammatory cytokines. However, the identification of factors that allow predicting the establishment of clinical disease is still lacking. Using an unbiased