Sodium Cellulose Phosphate in the Treatment of Hypercalciuric Children with Renal Stones

In the present study seven children, aged 5-16 years, who were admitted to the paediatric unit for nephorlithiasis had the 24 hour urinary calcium (UCa), Phosphorus (UP) and magnesium (UMg) excretions 8.2±2.5, 40.9±16.7 and 3.8±2.14 mg/kg, respectively. The UCa to urinary creatinine (UCr) concentration ratio (UCa/UCr), the UP/UCr and the UMg/UCr were 0.30 1.39 and 0.15 respectively. The values of serum Ca, P and Mg were 9.3±0.89, 4.6±0.27 and 2.28±0.56 mg/dl, respectively. After the oral administration of 10g sodium cellulose phosphate per day, the 24 hour urinary Ca, P and Mg excretions were 4.16±4.0, 24.9±7.5 and 2.16±2.0 mg/kg respectively. During the long term treatment the mean values of serum Ca, P and Mg were 9.8, 4.4 and 1.9 mg/dl, respectively. The patients did not have any new attacks of renal colic and no new renal stones were seen radiologically. All patients developed normally and no clinical and radiological findings of rickets were detected during the course of treatment lasting 6 months to 9 years.