Investigation and analysis of primary osteoporosis in postmenopausal women in Guangdong province

Objective To explore the change role of bone mineral density(BMD) and related factors in postmenopausal women in Guangdong province.Methods By investigating 1772 50～87 years old Guangdong inhabitants using questionnaire and BMD measurement with dual energy X-ray absorptiometry,274 postmenopausal osteoporosis cases were found.They were divided into 7 groups according to a 5-year-old division.The changes of BMD in the lumbar vertebrae(LV) and proximal femur(PF) and the correlation among body mass index(BMI),mass of fat,and BMD were analyzed.Results The prevalence of osteoporosis was 11.1～19.2% in various cities of Guangdong province,with 15.5% in the whole.The linear correlation coefficients between BMI and BMD of the femoral neck and total hip were 0.282 and 0.272(P0.05).The linear correlation coefficient between mass of fat and BMD of the lumbar vertebrae was 0.086(P0.05).Conclusion Bone mass loss of the lumbar vertebrae occurs obvious in women of 55～65 years old and 70～79 years old.Bone mass of the hip reduces quickly after the 65 years old.It is partially correlated between BMI and BMD of the hip.The correlation between mass of fat and BMD of the lumbar vertebrae is less.