Iodized contrast media. I. effector action on serum enzymes

In vitro studies were done to examine the effects of contrast media on blood enzymatic activities. The results observed are very significant: in the most simple cases they result in a competitive or mixed-type type inhibition of these enzymes. In systems which involve two substrates and two products a Bi-Bi ping-pong enzymatic mechanism is transformed in Bi-Bi random enzymatic mechanism.