The comparison of eosinophilic and non-eosinophilic stable COPD patients

Aim: We aimed to evaluated results of eosinophilic and non-eosinophilic-COPD patients. Methods: The study was recorded 202 stable-COPD patients from January 2015 to December 2015. Patients were divided into two group according to percentage of peripheral blood eosinophil as non-eosinophilic ≤2 % (n=80) and eosinophilic >2 % (n=122). Results: There was no found significant difference in terms of age, gander, comorbidity and exacerbations between groups. FEV1 values were significantly higher and CAT scores were significantly lower in eosinophilic group. Number and percentage of neutrophils were found higher and number and percentage of lymphocytes were found lower in non-eosinophilic patients. Platelet distribution width (PDW) and platelet-to-lymphocyte ratio (PLR) were significantly higher in non-eosinophilic patients compare to eosinophilic patients (Figure 1) Conclusion: Although we did not find any difference in terms of the number of exacerbations between eosinophilic and non-eosinophilic stable COPD patients. Our results showed that non-eosinophilic stable COPD patients are more symptomatic and have more airflow limitation.