Fenofibrate and losartan

The leader by Professor Bardin1 makes an excellent point. We could benefit from the hypouricaemic action of drugs that are not licensed for this use (for example, losartan and fenofibrate). Other drugs in common use may also have a uricosuric effect. For example, atorvastatin can reduce serum uric acid concentrations in patients with peripheral arterial disease or hyperlipidaemia.2–4 However, the mechanisms involved are not clear cut; we speculate that atorvastatin can increase renal …