Short-Term Exposure to PM2.5 Associated with Cardiovascular and Cerebrovascular Mortality in Mexico City from 2004-2013

Background. The association between short-term exposure to particles with aerodynamic diameter ≤2.5 μg (PM2.5) and daily mortality has been extensively described in cities of developed countries. Only limited evidence exists on short-term exposure to PM2.5 associated with specific causes of cardiovascular and cerebrovascular mortality in cities of developing countries.Methods. We obtained daily mortality records for Mexico City for 2004-2013 for all cardiovascular and cerebrovascular causes, ischemic heart disease, hemorrhagic and ischemic stroke in people ≥25 and ≥65 years old. Daily exposure to PM2.5 was assessed with estimates from a new hybrid spatiotemporal model using satellite measurements of Aerosol Optical Depth (AOD-PM2.5) and compared to PM2.5 measurements from ground-level monitoring stations with missing data estimated with Generalized Additive Models (GAM-PM2.5). We fitted Poisson regression models with distributed lags to evaluate the association between short-term ex...