MYB Labeling by Immunohistochemistry is More Sensitive and Specific for Breast Adenoid Cystic Carcinoma than MYB Labeling by FISH

Breast adenoid cystic carcinoma (ACC) is a primary breast carcinoma that, like salivary gland ACC, displays the t(6;9) translocation resulting in the MYB-NFIB gene fusion and immunopositivity for MYB by immunohistochemistry (IHC). However, it is not well established whether MYB immunoreactivity or r