Adjusting the starting dose of telaprevir according to renal function decreases adverse effects and affects the sustained virological response rate.

Daisuke Morihara,Hiroshi Watanabe,Kazuhide Takata,Hideyuki Iwashita,Naoaki Tsuchiya,Hideo Kunimoto,Shizuka Kuno,Atsushi Fukunaga,Kaoru Yotsumoto,Takashi Tanaka,Kunitoshi Sakurai,Genryu Hirano,Keiji Yokoyama,Shinya Nishizawa,Makoto Yoshikane,Akira Anan,Yasuaki Takeyama,Yuji Kitamura,Kaoru Iwata,Makoto Irie,Satoshi Shakado,Tetsuro Sohda,Shotaro Sakisaka

Adjusting the starting dose of telaprevir according to renal function decreases adverse effects and affects the sustained virological response rate.

2015

BackgroundTelaprevir (TVR) plays a major role in renal damage and anemia associated with TVR/pegylated interferon/ribavirin therapy for chronic hepatitis C. Adjusting the TVR starting dose may reduce these adverse effects. We aimed to determine whether adjusting the starting dose according to renal

Keywords:

Medicine
Diabetes mellitus
Renal function
Response rate (survey)
Telaprevir
Adverse effect
Anemia
Pathology
virological response
Internal medicine
Gastroenterology
Ribavirin
Pegylated interferon

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