Effect of rapamycin on lifespan in Drosophila.

Dear Editor,Aging in metazoans is a complex process associatedwith declining ability to respond to stress or maintainhomeostasis, and an increased risk of disease. Studies ofaginginseveralmodelsystemshaverevealedremarkablesimilarities in the cellular pathways influencing life-span determination among a range of organisms includ-ing fungi, invertebrates and mammals. The fruit fly