Glycoprotein storage disease: A new entity

Abstract Asymptomatic splenomegaly in an adult man prompted a detailed pathologic, histochemical and biochemical investigation. The results suggest the presence of a glycoprotein storage disease involving cells of the reticuloendothelial system. Results of further studies on family members have been consonant with an autosomal dominant pattern of inheritance but a recessive trait has not been ruled out completely.