Bilateral renal vein thrombosis can cause nephrotic range proteinuria

That patients with nephrotic syndrome are at an increased risk of developing renal vein thrombosis (RVT) is well established.1,2 However, whether RVT as an isolated event can cause nephrotic range proteinuria is not well documented. A 61-year-old Caucasian male, with history of hypertension, diabetes, obesity, deep venous thrombosis with placement of an inferior vena cava (IVC) filter (5 years ago), presented with an abrupt onset of gross hematuria and severe back pain. Pertinent laboratory results included an increased serum creatinine of 2.3 mg/dl (baseline 1.3 mg/dl). Computed tomography (CT) scan of the abdomen revealed bilateral renal vein thrombosis. The right renal vein was fully and the left partially occluded. The IVC filter was displaced and adjacent to the renal veins. …