Stress-rest MPI showing similar prevalence of CAD in asymptomatic African diabetic black patients and other racial groups

1727 Objectives To assess the changes in myocardial perfusion in asymptomatic African diabetic black patients and compare them with asymptomatic diabetic white and Indian patients. Methods The study included consecutive 94 asymptomatic African diabetic black patients and 50 asymptomatic diabetic white and Indian patients who were recruited from the outpatient diabetic clinic of the Johannesburg hospital. The QPS/QGS software was used to obtain resting and post stress left ventricular ejection fraction (LVEF). The means and percentages on study variables were obtained. The spearmen correlation coefficient was used to calculate correlations between variables. The Kruskal-wallis test was used to assess differences between different groups and Wilcoxon scores (rank sum) two-sided were used to measure differences within the groups. Results Participants from the asymptomatic African diabetic black group were younger than the participants from the asymptomatic diabetic white and Indian group with a mean age of 60 (SD±7.2) years vs 64 (SD±7.7) [p=0.003]. Fourteen percent of asymptomatic African black patients had evidence of ischaemia on MPI versus twenty eight percent of white and Indian asymptomatic participants. Fixed perfusion defects that were suggestive of CAD were noted in 20% of asymptomatic African black and 26% of asymptomatic white and Indian diabetic patients. No significant difference was noted on perfusion abnormalities seen in both asymptomatic African diabetic black patients and their white and Indian counterparts (p=0.47). Conclusions A high prevalence of CAD was noted in asymptomatic African diabetic black patients in a similar manner to other racial groups. The study has demonstrated the need to recommend stress MPI as a routine noninvasive investigation in the management of all asymptomatic diabetic patients