Article originalHypercholestérolémie familiale : un risque cardiovasculaire largement sous-estiméFamilial hypercholesterolemia: A largely underestimated cardiovascular risk
2017
Background
Familial hypercholesterolemia is a monogenic autosomal dominant dyslipidemia characterized by a permanent and isolated increase of cholesterol carried by low-density lipoproteins. The prevalence of its heterozygous form is estimated between 1/500 and 1/250, and in the absence of specific treatment, this form is responsible for an increase by a factor of 13 of the risk of premature coronary artery disease compared to patients non-affected by the disease.
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