The fibrin-derived peptide Bβ15- 42 is cardioprotective in a pig model of myocardial ischemia-reperfusion injury

Objective:The fibrin-derived peptide Bβ15–42 has been shown to reduce infarct size in rodent models of ischemia-reperfusion injury. To increase its potential for translation into the clinic, we studied the effects of Bβ15–42 in pigs, whose coronary anatomy is similar to that of humans. In addition,