Depuración de lactato como indicador pronóstico de mortalidad en pacientes con sepsis severa y choque séptico

OBJECTIVE. To determine if lactate clearance at twelve hours is an indicator of mortality in patients with sepsis severe and septic shock. M ETHODS: A prospective observational study was carried out in the Intensive Care Units (ICU) of the Arzobispo Loayza Hospital, Lima over a two year period. It included a cohort of patients by convenience with the diagnosis of sepsis severe and septic shock. They received catheterization central venous, arterial catheterization, pulmonary artery catheterization, vasoactives drugs, intubation and mechanical ventilation when were required. Vital signs, therapy installed, laboratory values, APACHE II and SOFA scores were obtained. Arterial lactate was obtained at admission and 6, 12 and 24 hours. The follow up was direct during hospitalization and by phone.after dis