Prevalence and factors associated with motoric cognitive risk syndrome in Community-dwelling Older Chinese: a cross-sectional study.

BACKGROUND: A recently proposed pre-dementia syndrome, motoric cognitive risk (MCR) syndrome, is characterized by cognitive complaints and slow gait and increases the risk of dementia and mortality. The aim of the present study was to explore the prevalence and factors with MCR in community-dwelling Chinese elderly. METHODS: Data from Ningbo Community Study on Aging (NCSA) recruited 953 Chinese community-dwelling participants aged >/=65 years from November 2016 to March 2017. Handgrip, five times sit to stand (FTSS) time and body composition, as well as comprehensive geriatric evaluation, were measured as potentially independent factors of MCR. RESULTS: The prevalence of MCR was 12.8% in men and 12.6% in women, high prevalence of MCR was not associated with age and sex. Multiple logistic regression analysis by sex showed that 1-SD increased in FTSS time in male and female was associated with a 45% (CI, 19%-76%; P<0.01) and 20% (CI, 9%-33%; P<0.01) higher odds of being MCR respectively, whereas handgrip strength inversely correlated with MCR in male (OR = 0.91, P = 0.02) but not in female (P = 0.06). Moreover, the relationship of arm fat mass and MCR had statistical significance in both sexes (OR = 1.69-1.77), but leg fat mass was just associated with MCR (OR = 1.56, P = 0.02) in men. CONCLUSIONS: Handgrip, five times sit to stand time and body composition are sex-specific associated with MCR in Chinese community-dwelling elderly. Our results on MCR are novel and should be considered as important information in future studies.