Arterial-hepatic vein glucose differences in normal and diabetic man after a glucose infusion at rest and after exercise.

Maehlum, S., Jervell, J. & Pruett, Esther D. R. Arterial-Hepatic Vein Glucose Differences in Normal and Diabetic Man after a Glucose Infusion at Rest and after Exercise. Scand. J. clin. Lab. Invest. 36, 415–422, 1976.The role of the liver in the elimination of infused glucose during recovery after exercise was studied in 5 normal and 4 juvenile diabetic males. The results were compared with those of a resting experiment. The subjects exercised on the bicycle ergometer at a work rate requiring about 70% of their max. Vo2. 0.5 g glucose per kg body weight was infused as a single injection 15 min after the cessation of exercise. Arterial-hepatic vein (a-hv) glucose and lactate differences were measured repetitively both during exercise and throughout the 79 min recovery period. During exercise the a-hv glucose differences were negative and increased more than sixfold in the diabetic subjects and more than tenfold in the non-diabetic subjects. After the glucose infusion the a-hv glucose differences were still ...