Abstract 17660: Prevalence and Prognosis of Early Ischemic Moderate to Severe Mitral Regurgitation After Primary Percutaneous Coronary Intervention

Background: Previously reported prevalence of ischemic mitral regurgitation (IMR) ranged from 15-64%, with 3-16% developing late moderate to severe IMR. However, most of these studies were performed in a heterogeneous population and prior to the routine use of PCI for STEMI. The objective of this study was to determine the prevalence and clinical prognostic implication of early IMR after primary PCI. Methods: Between January 2006 and July 2012, 174 consecutive patients referred to our tertiary care center for primary PCI, within 12 hours of symptoms onset, were included. Early post-MI (1-2 days) and late post-MI (244 days [85 - 533]) echocardiography data were analyzed. Patients were categorized according to their early post-MI IMR grading: no-MR group (≤ mild: n=155, 89%), MR group (≥ moderate: n=19, 11%). Results: Mean age was 63 ± 12 years, 79% were males and median follow-up was 366 days [34-582]. At the end of follow-up, IMR ≥ moderate was documented in 15% of our entire cohort. MR regression (≥ mode...