Polymerase chain reaction (PCR) for detection superantigenicity of Staphylococcus aureus isolated from psoriatic patients

Enterotoxigenic Stapylococcus aureus has an important role in triggering and maintenance psoriasis. This study was done to identify the frequency of the, genetic basis, enterotoxigenc S. aureus in psoriatic patient. Polymerase chain reaction (PCR) was performed for detect S. aureus enterotoxine A and B genes of bacteria isolated from psoriatic patients. S. aureus of psoriatic skin lesions have the enterotoxin genes (55%) significantly more than those from healthy skin of psoriatic patients (10%). Two genes were examined to be harbored by S. aureus isolates, namely enterotoxin A gene (22.5%) and enterotoxin B gene (10%) from psoriatic lesions, versus 10% of isolates from healthy skin of psoriatic patients that harbored enterotoxin B gene only. Enterotoxigenic S. aureus (A and B genes) isolated from psoriatic patients have an associated role with psoriatic lesions.