Abstract 1448: Serine 21 Phosphorylation of GSK-3{alpha} Mediates Myocyte Proliferation through CyclinD1/E2F Pathway under Pressure Overload

Serine(S)21/S9 phosphorylation of glycogen synthase kinase-3α (GSK-3α) and GSK-3β, respectively, by upstream kinases, such as Akt, inhibits GSK-3. In order to elucidate the role of S21/S9 phosphory...