Fructose acutely stimulates NKCC2 activity in rat thick ascending limbs by increasing surface NKCC2 expression

Gustavo R. Ares,Kamal M. Kassem,Pablo A. Ortiz

Fructose acutely stimulates NKCC2 activity in rat thick ascending limbs by increasing surface NKCC2 expression

2019

Gustavo R. Ares
Kamal M. Kassem
Pablo A. Ortiz

The thick ascending limb (TAL) reabsorbs 25% of the filtered NaCl through the Na+-K+-2Cl− cotransporter (NKCC2). NKCC2 activity is directly related to surface NKCC2 expression and phosphorylation. ...

Keywords:

Biochemistry
Diabetes mellitus
Cotransporter
Phosphorylation
Fructose
Transporter
Endocrinology
Biology
Internal medicine
Sugar
Kidney

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