Interval from the onset of transmitral flow to annular velocity is a marker of LV filling pressure.

Recently, the time interval between the onset of early diastolic transmitral flow velocity (E) and mitral annular velocity (e′) (TE-e′) was proposed as a new index representing left ventricular (LV) relaxation. A problem with the measurement of TE-e′ was that E and e′ could not be measured