Marginal growth increase, altered bone quality and polycystic ovaries in female prepubertal rats after treatment with the aromatase inhibitor exemestane.

Sandy A. van Gool,Jan M. Wit,Tineke M. De Schutter,Nora De Clerck,Andrei A. Postnov,Sandra Kremer Hovinga,Jaap van Doorn,Sergio Veiga,Luis Miguel Garcia-Segura,Marcel Karperien

Marginal growth increase, altered bone quality and polycystic ovaries in female prepubertal rats after treatment with the aromatase inhibitor exemestane.

2010

Sandy A. van Gool
Jan M. Wit
Tineke M. De Schutter
Nora De Clerck
Andrei A. Postnov
Sandra Kremer Hovinga
Jaap van Doorn
Sergio Veiga
Luis Miguel Garcia-Segura
Marcel Karperien

Background: Aromatase inhibition has been proposed as a potential approach for growth enhancement in children with short stature, but detailed animal studies are lacking. A

Keywords:

Osteopenia
Internal medicine
Aromatase
Diabetes mellitus
Exemestane
Short stature
Estrogen
Endocrinology
Aromatase inhibitor
Animal studies
Medicine
polycystic ovary

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