The effects of devascularization procedure on hepatic hemodynamics and hepatic function

Objective To investigate the effects of devascularization procedure on hepatic hemodynamics and hepatic function of portal hypertensive patients.Methods The portal venous flow (PVF) and hepatic arterial flow (HAF) were measured with Doppler ultrasonic instrument in 25 patients with portal hypertension.The free portal venous pressure (FPP) was measured by manometric method.The hepatic function was measured by indocynine green retention rate at 15 minutes during perioperative period. Results It was found that PVF was decreased from (1 323±388) ml/min preoperatively to (895±262) ml/min postoperatively ( P 0 001);HAF increased from (370±70) ml/min preoperatively to (485±123) ml/min postoperatively ( P 0 001);FPP decreased from (28±4) mmHg preoperatively to (25±4) mmHg postoperatively ( P 0 05);R 15ICG increased from (19±7)% preoperatively to (21±7)% postoperatively ( P 0 05).Conclusions PVF was decreased after the devascularization,but the increased HAF and the decreased portal system shunt postoperatively were beneficial to the maintenance of the function of cirrhotic liver.