Abstract 19025: Frailty Assessment in Early Invasive Percutaneous Coronary (PCI) Management of Non-ST-Elevation Acute Coronary Syndromes (NSTE-CS): Is Clinical Perception of Frailty Enough?

Introduction: As our population ages, the role of frailty in CAD is increasingly clinically relevant. Approximately 12.4% of the US population with CAD is 65 years and older. It has been noted that females and the elderly are treated less aggressively in the setting of NSTE-CS. Hypothesis: Subjective assessment of frailty compared to objective measure of frailty shows a significant difference in PCI management of NSTE-CS in women versus men, in the elderly population. Methods: We conducted a retrospective review of patients 65 and older, from March 1, 2015 to December 31, 2015 that were admitted to an urban, multiracial tertiary care center for unstable angina or NSTEMI (n = 120). Primary endpoint of measured frailty compared with subjective assessment of frailty amongst the genders was assessed in the setting of NSTE-CS. Secondary endpoint of outcomes post - early intervention PCI in the frail were also assessed. Results: Females presented with a higher GRACE risk score compared with men with a mean of 132 ± 30, p Conclusions: Subjective and objective measure of frailty showed no statistically significant difference in our sample population. Gender showed no statistical difference in frailty scores or outcomes post PCI. Objectively high measures of frailty were associated with poorer outcomes overall with or without early PCI.