SAT0348 HOW FREQUENT IS NEUROPATHIC PAIN COMPONENT IN PATIENTS WITH SPONDYLOARTHRITIS

2019 
Background: Criteria to define inflammatory back pain in Spondyloarthritis (SA) are multiple. Although neuropathic pain component was known to be part of disease symptoms, it has been rarely assessed. Objectives: The aim of this study was to determine the prevalence of the neuropathic pain component in SA patients and secondarily, to detect correlation with the disease duration, activity scores and functional impairment. Methods: A cross-sectional study including patients with radiographic axial SA defined by ASAS criteria was conducted. Patients were questioned about their neuropathic pain using painDETECT questionnaire and Douleur Neuropathique en 4 Questions (DN4) interview. Further information about disease characteristics, activity (BASDAI, ASDASCRP) and functional (BASFI) scores were assessed the same day. Statistical analysis, was performed by Khi2-test for qualitative variables and Student-test for quantitative variables. A p value ≤0.05 was considered significant. Results: Forty patients were included. The average age was about 41 years old (±12.9) and the sex ratio was 12.3 (H/F). The mean disease duration was 10.7±6.9 years. Most of patients suffered from back pain and the visual analogic scale pain scale was about 3.78±2.5. The mean BASDAI score was 2.75±2.3 and the mean ASDASCRP was 2.24±1.07. The average BASFI score was 2.57±2.5. Neuropathic pain component was noted only in 7.5% of patients by DN4 interview (≥4/10) and in 10% of patients by pain DETECT questionnaire. As expected, patients with DN4≥4 were correlated to the visual analogic scale pain (p=0.04) and female gender (p=0.07). But no relation was found with the type of SA or the disease activity or the functional scores. Conclusion: Neuropathic pain component was noted only in 10% of SA in our work. Positive correlation was found with visual analogic scale pain and female gender. Larger studies are needed to assess this type of pain since therapeutic strategy may be affected. Disclosure of Interests: None declared
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