DOFETILIDE ASSOCIATED QT PROLONGATION: ACTUAL VERSUS IDEAL BODY WEIGHT TO CALCULATE DOSING

Background: Dofetilide is used to treat patients with atrial fibrillation, with recommended dosing based on the Cockcroft-Gault formula using actual body weight (ABW). Dose reduction or discontinuation may be necessary for excessive QT prolongation. We investigated whether initial dosing based on