Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial.

Mark J. Peters,G.A.L. Jones,Daisy Wiley,Jerome Wulff,Padmanabhan Ramnarayan,Samiran Ray,David Inwald,Michael P. W. Grocott,Michael J. Griksaitis,John Pappachan,Lauran O’Neill,Simon Eaton,Paul R Mouncey,David A. Harrison,Kathryn M Rowan

Conservative versus liberal oxygenation targets in critically ill children: the randomised multiple-centre pilot Oxy-PICU trial.

2018

Mark J. Peters
G.A.L. Jones
Daisy Wiley
Jerome Wulff
Padmanabhan Ramnarayan
Samiran Ray
David Inwald
Michael P. W. Grocott
Michael J. Griksaitis
John Pappachan
Lauran O’Neill
Simon Eaton
Paul R Mouncey
David A. Harrison
Kathryn M Rowan

Background Oxygen saturation monitoring for children receiving respiratory support is standard worldwide. No randomised clinical trials have compared peripheral oxygen saturation (SpO2) targets for critically ill children. The harm of interventions to raise SpO2 to > 94% may exceed their benefits.

Keywords:

Clinical trial
Intensive care medicine
Harm
Oxygenation
Oxygen saturation
Psychological intervention
Peripheral oxygen saturation
Medicine
Anesthesiology
Anesthesia
intensive care
Gestation
Confidence interval
Interquartile range
Adverse effect
Internal medicine

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