Clinical patterns of Pneumocystis Jirovecii in HIV and non-HIV patients

Introduction and Objectives: Pneumocystis jirovecii pneumonia is a life-threatening opportunistic infection that affects immunodeficient patients, including HIV, malignant tumors, immunosuppressive treatment, prolonged corticosteroid therapy and organ transplantation. The aim of the study is contrasting the different clinical patterns, complications and death between HIV and non-HIV patients. Material and Methods: Observational study of Pneumocystis jirovecii pneumonia supported cases in patients with HIV infection and immunocompromised patients of different etiology from January 2014 and July 2018. Results: We included 74 patients: 41 of them without HIV, 57% males, age 58,4 ±13 years, Charlson Index 4 points (2-6), chronic use of corticoids 81%, previous chemotherapy 60%. And 33 patients with HIV, 62% males, age 46,4 ±9 years, Charlson Index 1 point (0-2). In table 1, both groups’ characteristics are compared. Conclusions: Non-HIV patients presented a higher rate of radiological consolidation, number of complications and admissions to Critical Care Unit and less percentage of survival rates.