Original InvestigationVagus Nerve Stimulation for the Treatment of Heart Failure: The INOVATE-HF Trial
2016
Background
Heart failure (HF) is increasing in prevalence and is a major cause of morbidity and mortality despite advances in medical and device therapy. Autonomic imbalance, with excess sympathetic activation and decreased vagal tone, is an integral component of the pathophysiology of HF.
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