Efficacy and toxicity of concurrent chemoradiotherapy in patients with advanced oropharyngeal squamous cell carcinoma

Makiko Mori,Mamoru Tsukuda,Hideki Matsuda,Choichi Horiuchi,Takahide Taguchi,Masahiro Takahashi,Goshi Nishimura,Masanori Komatsu,Tatsuo Niho,Naoko Sakuma,Asako Miyakoshi,Yasuhiro Isono,Sayaka Iwahana

Efficacy and toxicity of concurrent chemoradiotherapy in patients with advanced oropharyngeal squamous cell carcinoma

2011

Makiko Mori
Mamoru Tsukuda
Hideki Matsuda
Choichi Horiuchi
Takahide Taguchi
Masahiro Takahashi
Goshi Nishimura
Masanori Komatsu
Tatsuo Niho
Naoko Sakuma
Asako Miyakoshi
Yasuhiro Isono
Sayaka Iwahana

Purpose The aim of this study was to evaluate the feasibility and toxicity of concurrent chemoradiotherapy (CCRT) with docetaxel, cisplatin (CDDP) and 5-fluorouracil (5-FU) (TPF regimen) or with CDDP, 5-FU, methotrexate and leucovorin (PFML regimen) in previously untreated patients with advanced oropharyngeal squamous cell carcinoma (SCC).

Keywords:

Regimen
Cisplatin
Chemoradiotherapy
Methotrexate
TPF Regimen
Oncology
Docetaxel
Internal medicine
Oropharyngeal squamous cell carcinoma
Toxicity
Medicine
concurrent chemoradiotherapy

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