Prediction of degree of residual stenosis in coronary thrombolysis

In order to predict the residual stenosis in coronary thrombolysis, the factors easily obtained from clinical history—age, gender, history of angina before acute myocardial infarction (AMI), family history, hypertension, diabetes, hypercholesterolemia, smoking, and interval between onset of AMI and recanalization—were observed in 114 patients with successful coronary thrombolysis. In 55 patients with angina before AMI, 29 patients had residual stenosis ≥75% and 26 patients had residual stenosis <75%. In 59 patients without angina before AMI, 15 patients had residual stenosis ≥75%, and 44 patients had residual stenosis <75 %. The presence or absence of angina before AMI was the main variable that discriminated the groups of residual stenosis of more or less than 75 %, which was the only significant independent variable to predict the residual stenosis. These data suggest that the presence of angina pectoris before AMI is likely to be associated with a significant degree of residual stenosis after thrombolysis.