Abstract 12454: Vildagliptin Attenuates Cardiac Hypertrophy and Improves Ventricular Efficiency Through FGF21 Expression in Pressure-overloaded Mouse Heart

Nozomi Furukawa,Norimichi Koitabashi,Hiroaki Sunaga,Masaru Obokata,Yogi Umbarawan,Mas Rizky A. A. Syamsunarno,Aiko Yamaguchi,Hiroki Matsui,Tomoyuki Yokoyama,Masahiko Kurabayashi

Abstract 12454: Vildagliptin Attenuates Cardiac Hypertrophy and Improves Ventricular Efficiency Through FGF21 Expression in Pressure-overloaded Mouse Heart

2016

Nozomi Furukawa
Norimichi Koitabashi
Hiroaki Sunaga
Masaru Obokata
Yogi Umbarawan
Mas Rizky A. A. Syamsunarno
Aiko Yamaguchi
Hiroki Matsui
Tomoyuki Yokoyama
Masahiko Kurabayashi

Introduction: Basic and clinical studies have shown that Dipeptidyl Peptidase-4 (DPP-4) inhibitor an anti-hyperglycemic agent, has cardioprotective effects through angiogenesis, anti-hypertrophy or...

Keywords:

Fibrosis
Ventricular remodeling
Vildagliptin
Angiogenesis
Gene expression
FGF21
Internal medicine
Medicine
Cardiology
Muscle hypertrophy
Diabetes mellitus
Mouse Heart

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