AB1352-HPR INVESTIGATION OF EFFECT OF DISEASE AND RELATED FACTORS IN INDIVIDUALS WITH FIBROMYALGIA

Background Fibromiyalgia (FM), one of the most common rheumatologic disorders, is characterized by widespread pain in the body, sensitivity in the certain anatomical regions, fatigue, sleep disorders and reduced pain threshold, uncommon and extra-articular rheumatism disease (1). It has been reported that impairments in functional capacity and quality of life cause significant limitations in individuals with FM (2). Objectives The aim of this study was to examine the effect of disease and to investigate the factors associated with the disease in individuals with FM. Methods In our study, 334 voluntary individuals with FM (324 famele,10 male) who applied to Pamukkale University Department of Internal Medicine, Department of Rheumatology were diagnosed according to 2010 American College of Rheumatology criteria whom participated in the study with the mean age of 47,55±10.46 (years). Fibromyalgia Impact Questionnaire (FIQ) was used to determine the effect of disease, Beck Depression Inventory (BDI) and Beck Anxiety Inventory (BAI) for emotional status and Pittsburgh Sleep Quality Index (PSQI) for sleep quality, right after demographic information and disease related data were recorded. Multiple regression analysis were used to examine the factors related to disease activity. Results High body mass index (B=.121, p=0.023), high tender point score (B=.427, p=0.000), high depression score (B=.350, p=0.00), high anxiety score (B=.258, p=0.000) and poor sleep quality (B=.157, p=0.002) corresponded to the higher FIQ score. However, age (B=-.019, p=0.716), level of education (B=.009, p=0.858) and disease duration (B=.054, p=0.331) did not significantly affect FIQ. Conclusion As a result of our study the progress of body mass index in individuals with FM, increase in number of tender points, poor sleep quality, depression and anxiety were among the factors affecting the disease. Therefore, these factors must be considered in order to reduce the severity of the disease in individuals with FM. References [1] Wolfe F, Ross K, Anderson J, Russell IJ, Hebert L. The prevalence and characteristic of fibromyalgia in the general population. Arthritis Rheum 1995;38:19-28. [2] Arnold LM, Crofford LJ, Mease PJ, et al. Patient perspectives on the impact of fibromyalgia. Patient Educ Couns 2008a;73:114-20. Disclosure of Interests None declared