Abstract 14016: Severity Assessment of Brain Damage With rSO2 monitoring for Extracorporeal Cardiopulmonary Resuscitation After Out-of-hospital Cardiac Arrest

Introduction: Decisions regarding extracorporeal cardiopulmonary resuscitation (E-CPR) for patients after out-of-hospital cardiac arrest (OHCA) are difficult to make. Hypothesis: We hypothesized that regional brain oxygen saturation (rSO2) value monitoring in the emergency room was useful for speculating on brain damage severity for prognostication for E-CPR after OHCA. Methods: The J-POP registry is a prospective multicenter cohort study to test whether rSO2 predicts neurological outcomes after nontraumatic OHCA. We measured rSO2 values in OHCA patients immediately after hospital arrival with a near-infrared spectrometer placed on the forehead. The primary endpoint was neurological outcome (cerebral performance category: 1, 2) 90 days after OHCA. Results: We consecutively enrolled 1,921 OHCA patients. After 90 days, 79 (4%) patients had good neurological outcomes and a median lower rSO2 level of 15% (95% confidence interval (CI): 15-20%). Receiver operating curve analysis indicated an optimal rSO2 cutoff...