Observation on Therapeutic Effect of Indwelling Nasojejunal Feeding Tube Through Gastroscope in Treatment of Severe Acute Pancreatitis

2011 
Objective:To observe the therapeutic effect of indwelling nasojejunal feeding tube through gastroscope in patients with severe acute pancreatitis(SAP).Methods:Fifty patients were randomized divided into two groups:① 26 cases of total parenteral nutrition(TPN) group underwent routine therapy:fasting,gastrointestinal decompression,acid suppressing,anti-infection,somatostatin,and parenteral nutrition,etc.② On the basis of routine therapy,24 cases of enteral nutrition(EN) group were indwelled nasojejunal feeding tube through gastroscope about 3 days after admission.Then,the parenteral nutrition was gradually stopped and switched to EN.Changes of levels of patients' hemoglobin,serum total protein,serum albumin and blood calcium were compared before treatments and 10,20 days after treatments.Average length of hospital stay and costs were calculated,and the rate of infection and mortality were observed.Results:Patients in EN group underwent one-time catheterization successfully without obvious complications.Level of hemoglobin was elevated obviously in EN group than that in TPN group 20 days after treatment(P0.05).Hospital stay,hospital costs and rate of infection were obviously lower in EN group than those in TPN group(P0.05).Conclusions:Indwelling nasojejunal feeding tube through gastroscope is effective and safe in patients with SAP.
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