CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH NON ALCOHOLIC FATTY LIVER DISEASE

2013 
INTRODUCTION: Non-alcoholic fatty liver disease (NAFLD), comprising a spectrum of condition ranging from pure steatosis to steatohepatitis and cirrhosis. Increasing the recognition of the importance of NAFLD and its strong relationship with metabolic syndrome has stimulated interest in the possible role of NAFLD in the development of cardiovascular disease. AIMS AND OBJECTIVE: To study the relationship between 1.Cardiovascular diseases and diabetic patients having non-alcoholic fatty liver.2.Cardiovascular diseases in obese and hypertensive patients having non-alcoholic fatty liver. MATERIALS AND METHODS: The study was conducted on 50 diagnosed patients of NAFLD, with objective to identifying the association of various cardiovascular risk factor associated with it.The study was design to study the association or co-relation between NAFLD to various cardiovascular risk factor, diagnosed by standard laboratory, imaging and by physical measurement. We used the standard value of p and chi square for establishing statistically significant association between multiple variables in our study. RESULTS: In our study out of 50 patients, 30 male and 20 female patients, 05 males and 03 females in group A, 20 males and 13 females in group B and 05 male and 04 female patients in group C, the p value (≤0.05) and chi square value (=15). 50 patients of NAFLD were randomized into two groups, group A (NAFLD with obesity, p value 0.0048, chi value of 10.667) and group B (NAFLD without obesity p = (NA) and chi square value = (NA). Patients of NAFLD were randomized into two groups, group A (NAFLD with diabetes, p value 0.0002 and chi value of 16.8) and group B (NAFLD without diabetes, p value = (NA) and chi square value =NA).Patients of NAFLD were randomized into two groups, group A (NAFLD with Hypertension p value 0.0009 and chi value of 14) and group B (NAFLD without Hypertension disease p value is (NA) and chi square value is (NA). CONCLUSION: We hereby conclude from the present study that NAFLD is not only the disease of liver; rather it has statistically high significant association with cardiovascular disease (ischemic heart disease), obesity, diabetes, older age group, male sex, metabolic syndrome etc.
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