An Interesting Case of Adult Cyclic Vomiting Syndrome and Its Long Term Management.

Cyclic vomiting syndrome is an increasingly recognized cause of nausea and vomiting in adults. We report this case of a 40 year old female with recurrent episodes of intractable nausea and vomiting for more than 4years. Her symptoms persisted for 3–5 days on an average and then resolved spontaneously, only to return after periods of time ranging from few weeks up to a month or two. After an extensive workup, which failed to determine any causative explanation for her symptoms, she was diagnosed with cyclic vomiting syndrome. Her episodes of vomiting were successfully terminated with the use of ondansetron for aborting episodes initially, later continued with amitriptyline. In this case, we highlight that amitriptylline4 effectively aborted symptoms in an adult patient with cyclic vomiting syndrome, increasingphysician’s awareness of adult cyclic vomiting syndrome may improve care of patients suffering from this debilitating condition.