Differential diagnosis and treatment of diabetes mellitus associated with Cushig’s disease

Diabetes mellitus associated with endogenic hypercortisolism is one of the most frequent symptoms of Cushing’s disease and may mask other implications. Achievement of the disease’s remission not always leads to complete involution of its complications. The new glucose-lowering drugs can exert a complex positive impact in patients with hypercortisolemic comorbidities. To treat diabetes mellitus associated with the central hypercortisolism groups of dipeptidyl peptidase 4 inhibitors and sodium-glucose co-transporter-2 inhibitors should be taken into account.