Metabolomics in Angiotensin II-Induced Cardiac Hypertrophy

Eero Mervaala,Agnieszka Biala,Saara Merasto,Juha Lempiäinen,Ismo Mattila,Essi Martonen,Ove Eriksson,Marjut Louhelainen,Piet Finckenberg,Petri Kaheinen,Dominik Müller,Friedrich C. Luft,Risto Lapatto,Matej Orešič

Metabolomics in Angiotensin II-Induced Cardiac Hypertrophy

2010

Eero Mervaala
Agnieszka Biala
Saara Merasto
Juha Lempiäinen
Ismo Mattila
Essi Martonen
Ove Eriksson
Marjut Louhelainen
Piet Finckenberg
Petri Kaheinen
Dominik Müller
Friedrich C. Luft
Risto Lapatto
Matej Orešič

Angiotensin II (Ang II) induces mitochondrial dysfunction. We tested whether Ang II alters the "metabolomic" profile. We harvested hearts from 8-week-old double transgenic rats harboring human reni ...

Keywords:

Endocrinology
Diabetes mellitus
Angiotensin II
Internal medicine
Medicine
Oxidative stress
Transgenic Rats
Metabolomics
Peptide hormone
Muscle hypertrophy
Endothelial dysfunction
Gene expression
Calorie restriction
Mitochondrial biogenesis

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