Beta-endorphins in essential blepharospasm

The effect of the administration of adrenergic and serotoninergic substances on beta-endorphins was evaluated in four patients with essential blepharospasm. The lack of beta-endorphin release following administration of adrenergic agents demonstrated that this aminergic action on the hypothalamus-pituitary adrenal axis is modified in the presence of the essential blepharospasm.