Screening of Alternative Drugs to the Tumor Suppressor miR-375 in Esophageal Squamous Cell Carcinoma Using the Connectivity Map

Yuka Isozaki,Isamu Hoshino,Yasunori Akutsu,Naoyuki Hanari,Mikito Mori,Takanori Nishimori,Kentaro Murakami,Naoki Akanuma,Takeshi Toyozumi,Masahiko Takahashi,Hiroshi Suito,Nobuyoshi Takeshita,Tetsuro Maruyama,Akane Suzuki,Toshinori Nakayama,Hisahiro Matsubara

Screening of Alternative Drugs to the Tumor Suppressor miR-375 in Esophageal Squamous Cell Carcinoma Using the Connectivity Map

2014

Yuka Isozaki
Isamu Hoshino
Yasunori Akutsu
Naoyuki Hanari
Mikito Mori
Takanori Nishimori
Kentaro Murakami
Naoki Akanuma
Takeshi Toyozumi
Masahiko Takahashi
Hiroshi Suito
Nobuyoshi Takeshita
Tetsuro Maruyama
Akane Suzuki
Toshinori Nakayama
Hisahiro Matsubara

Objective: The aim of this study was to identify alternative compounds to the tumor suppressor miR-375 using the connectivity map (CMAP) and to validate the antit

Keywords:

Carcinoma
Metformin
Immunology
Cell
Pathway analysis
Medicine
Rosiglitazone
Mir-375
Oncology
Suppressor
Diabetes mellitus
esophageal squamous cell carcinoma
Internal medicine

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