Glycosylated hemoglobin as a predictor of mortality in severe pneumonia by COVID-19.

Objective Determine whether the levels of glycated hemoglobin (HbA1c) measured on admission to the intensive care unit (ICU) are associated with mortality in patients with severe SARS-CoV-2 pneumonia with invasive mechanical ventilation. Design cohort study, retrospective, observational. A single center. Place ICU of a second level care hospital. Patients Severe SARS-CoV-2 pneumonia confirmed with IMV since admission to the ICU. Interventions none. Results a total of 56 patients with severe pneumonia, confirmed with SARS-CoV-2, all with IMV. The group with HbA1c 500 U/L, OR 3.65 (95% CI 1.18-11.29), HbA1c ≥ 6.5%, OR 3.12 (95% CI 1.01-9.6), SAH, OR 3.12 (95% CI 1.01-9.5), use of vasopressor, OR 0.2 (95% CI 0.05-0.73), diabetes was not statistically significant. Conclusion the 28-day probability of survival in patients with severe SARS-CoV-2 pneumonia with IMV in the ICU is lower when the HbA1c level is ≥ 6.5% on admission.