CLINICAL APPROVED LIPOSOMAL FORMULATIONS: A OVER VIEW

Liposomes are vesicular colloidal carrier system composed of phospholipids bilayer encapsulate aqueous compartments. Since 1960’s liposomes used as therapeutic tools for the delivery of bioactives.Hence number of liposomal formulations available in the market as compare to other carrier system such as nanoparticles,dendrimers etc. The structure and composition of liposomes has a great impact on their properties like biocompatibility,bioactive payload, immuo neutralization,absence of cytotoxicity and hemolytic toxicity. As a result of their unique liposomes are suitable for a wide range of biomedical and industrial applications.The paper gives a concise review of liposomes formulation physico-chemical properties and their clinical application in vaccination, tumor targeting, immunomodulation, topical delivery of bioactives for skin care,gene and antisense therapy. The goal of this review is to provide a short outline of the properties of liposomes and market research analysis of liposomes clinical approved products.