Automatic Brain Tumor Segmentation with Domain Adaptation.

Deep convolution neural networks, in particular, the encoder-decoder networks, have been extensively used in image segmentation. We develop a deep learning approach for tumor segmentation by combining a modified U-Net and its domain-adapted version (DAU-Net). We divide training samples into two domains according to preliminary segmentation results, and then equip the modified U-Net with domain adaptation structure to obtain a domain invariant feature representation. Our proposed segmentation approach is applied to the BraTS 2018 challenge for brain tumor segmentation, and achieves the mean dice score of 0.91044, 0.85057 and 0.80536 for whole tumor, tumor core and enhancing tumor, respectively, on the challenge’s validation data set.