Positive end-expiratory pressure can increase brain tissue oxygen pressure in hypoxemic severe traumatic brain injury patients

Brain tissue oxygen pressure (PtiO2) reflects brain oxygenation and is a useful tool in traumatic brain injury (TBI) patients. Increases in inspired oxygen fraction (FiO2) are related to improvement on PbrO2, but other approaches that aim to improve oxygenation, like increasing positive-end expiratory pressure (PEEP), were not deeply evaluated in humans.