Novel inhibitors of nicotinamide phosphoribosyl transferase and their evaluation in combination with bortezomib.

Murali Ramachandra,Anirudha Lakshminarasimhan,Dinesh Chikkanna,Vinayak Khairnar,Sunil Kumar Panigrahi,Anuradha Ramanathan,Sumalatha Rani,Narasimha Rao K,Karthikeyan S,Kishore Narayanan,Sreevalsam Gopinath,Raghuveer Ramachandra,Subramanya Hosahalli,Chetan Pandit

Novel inhibitors of nicotinamide phosphoribosyl transferase and their evaluation in combination with bortezomib.

2014

Murali Ramachandra
Anirudha Lakshminarasimhan
Dinesh Chikkanna
Vinayak Khairnar
Sunil Kumar Panigrahi
Anuradha Ramanathan
Sumalatha Rani
Narasimha Rao K
Karthikeyan S
Kishore Narayanan
Sreevalsam Gopinath
Raghuveer Ramachandra
Subramanya Hosahalli
Chetan Pandit

e19566 Background: Nicotinamide phosphoribosyl transferase (NAMPT) is the enzyme that catalyzes the rate limiting step in the salvage pathway of Nicotinamide Adenine Dinucleotide (NAD) biosynthesis...

Keywords:

Bortezomib
Pathology
Cancer research
Nicotinamide
Transferase
Medicine
Nucleotide salvage
Biochemistry
phosphoribosyl transferase
Nicotinamide adenine dinucleotide
Biosynthesis
NAD+ kinase
Enzyme

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